周子雄 副教授
硕士生导师，病理学系副主任
邮箱：zzxpathology @snapian.net
个人简介
周子雄，男，副教授，硕士生导师，福建省高层次引进人才（境外C类）。博士毕业于韩国全北国立大学，现就职于熟女a片 病理学系。承担研究生、本科生、海外医学生等的病理学理论课和实验课授课，并长期从事g肝脏病理的研究工作。任Exploration、Metabolism & Target Organ Damage青年编委，为Experimental & Molecular Medicine和Phytomedicine等30余本SCI杂志审稿。近5年以第一或通讯作者在Phytomedicine、American Journal of Pathology、Toxicology等国际经典杂志发表SCI论文18篇。研究成果被Nature Reviews Gastroenterology & Hepatology，Signal Transduction and Targeted Therapy，Science Translational Medicine，Gastroenterology，Cell Death and Differentiation，Nature Communications等顶级期刊多次引用。
研究领域
探究代谢障碍相关性脂肪性肝炎（MASH）和肝纤维化的致病机理和治疗靶点。
主持/参与的项目
主持国自然和省自然等多项基金项目。
科研成果
部分文章列表如下：
1. Zixiong Zhou, Jing Qi, Jing Zhao, et al. Orostachys japonicus ameliorates acetaminophen-induced acute liver injury in mice. Journal of Ethnopharmacology, 265 (2021) 113392.
2. Zixiong Zhou, Jing Qi, Jing Zhao, et al. Exogenous activation of toll-like receptor 5 signaling mitigates acetaminophen-induced hepatotoxicity in mice. Toxicology Letters. 342 (2021) 58–72.
3. Zixiong Zhou; Wu yong; Hua Wenxi; et al. (2022). Sappanone A ameliorates acetaminophen-induced acute liver injury in mice. Toxicology. 2022 Oct; 480:153336
4. Zixiong Zhou; Jing Qi; Yajiao Wu; Chutao Li; Wenqiang Bao; Xiaohuang Lin; An Zhu. (2023). Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury. Antioxidants, 2023, 12(4): 949-954.
5. Kexin Qiu; Yan Pan; Weizhi Huang; Mengyuan Li; Xueqing Yan; Zixiong Zhou#; Jing Qi#. (2023). CXCL5 Promotes Acetaminophen-Induced Hepatotoxicity by Activating Kupffer Cells. International Journal of Molecular Sciences, 2023, 24(15): 12180-12186.
6. Zixiong Zhou, Xijie Yu, Yuqing Chen, et al. (2022). Inhibition of the B7-H3 immune checkpoint limits hepatocellular carcinoma progression by enhancing T lymphocyte-mediated immune cytotoxicity in vitro and in vivo. Clin Transl Oncol. 2023 Apr;25(4):1067-1079.
7. Ruonan Chen*; Zixiong Zhou*; Yi Chen; Aimin Huang; Lihong Chen. (2023) Evaluation of transcriptomic molecular classification, biological behavior and clinicopathological features in hepatocellular carcinoma. Expert Review of Molecular Diagnostics, 2023(2169072). 8. Jing Qi; Lanqian Li; Xueqing Yan; Wenxi Hua; Zixiong Zhou#. (2023). Sappanone A Alleviates the Severity of Carbon Tetrachloride-Induced Liver Fibrosis in Mice. Antioxidants, 2023, 12(9): 1718-1724.
9. Jing Qi; Xueqing Yan; Lanqian Li; Kexin Qiu; Weizhi Huang; Zixiong Zhou#. (2023). CXCL5 promotes lipotoxicity of hepatocytes through upregulating NLRP3/Caspase-1/IL-1β signaling in Kupffer cells and exacerbates nonalcoholic steatohepatitis in mice. Int Immunopharmacol. 2023 Oct: 123:110752.
10. An Zhu*, Xueqing Yan*, Mengting Chen*, Yifan Lin, Lanqian Li, Yufei Wang, Jiabin Huang, Jiale He, Mengchen Yang, Wenxi Hua, Kunqi Chen#, Jing Qi#, Zixiong Zhou#. (2025) Sappanone A alleviates metabolic dysfunction-associated steatohepatitis by decreasing hepatocyte lipotoxicity via targeting Mup3 in mice. Phytomedicine 136 (2025) 156341.
指导学生情况
已毕业研究生：李岚倩（国奖获得者，校级优秀毕业生）；
在读研究生：黄嘉彬，曾晰，谭正宜，刘旭扬，何涛；
已毕业本科生：何家乐（22级基础专业，国奖获得者，校级优秀毕业生，保研至北京协和医学院），邱可欣（20级临床专业，保研至福医大附属协和医学院），潘言（20级麻醉专业，考研至浙江中医药大学），黄伟智（20级临床专业，考研至福医大附属第二临床医学院）；
在读本科生：李叶浩民（21级基础专业，挑战杯-省级三等奖），杨锦保（21级临床5+3，生命科学竞赛-科学探究类-全国三等奖），袁经论（22级基础专业基础专业，挑战杯-省级三等奖），陈卓彦（24级基础专业），郭宇琪（24级基础专业）。
（更新于2025年7月）
