周莹  高级实验师

硕士生导师

联系邮箱：[email protected]

个人简介

周莹，女，医学博士（国家纳米科学中心联合培养），硕士生导师，美国华盛顿大学医学院访问学者，福建省级高层次人才C类，任Exploration、VIEW等期刊青年编委，担任Exploration、Journal of Alzheimer's Disease等期刊审稿人。

研究领域

长期从事脑肿瘤及神经退行性疾病诊疗相关的课题研究，致力于开发基于高通量微流控芯片体系，构建高效的多肽识别分析平台，实现重大神经系统疾病的早期、精准、特异检测，以及构建功能化纳米药物的治疗研究。

1.神经系统疾病的诊疗研究

2.神经系统疾病的发病机制研究

主持/参与的项目

1.国家自然科学基金青年科学基金项目，30万元，2025.01-2027.12，主持

2.福建省科技创新联合资金项目，15万元，2024.01-2026.12，主持

3.福建省自然科学基金面上项目，7万元，2022.08-2025.08，主持

4.国家自然科学基金国家重大科研仪器研制项目，725万元，2021.01-2025.12，参与

5.福建省卫生健康重大科研专项项目，300万元，2025.01-2028.12，参与

科研成果

1.Ying Zhou#, Guoen Cai#, Yuanzhuo Wang#, Yuxin Guo#, Zhimin Yang, Anqi Wang, Yongshou Chen, Xuejie Li, Xiaochun Chen*, Zhiyuan Hu*, Zihua Wang*. Microarray Chip-Based High-Throughput Screening of Neurofilament Light Chain Self-Assembling Peptide for Noninvasive Monitoring of Alzheimer's Disease. ACS Nano, 2024, 18 (28): 18160-18175. (IF: 16，中科院1区Top)

2.Ying Zhou#, Yuxin Guo#, Lufei Chen#, Xiaoli Zhang#, Wei Wu, Zhimin Yang, Xuejie Li, Yuanzhuo Wang, Zhiyuan Hu*, Zihua Wang*. Co-delivery of phagocytosis checkpoint and STING agonist by a Trojan horse nanocapsule for orthotopic glioma immunotherapy. Theranostics, 2022, 12 (12): 5488-5503. (封面文章，IF: 12.4，中科院1区Top)

3.Ying Zhou#, Long Wang#, Lufei Chen#, Wei Wu#, Zhimin Yang, Yuanzhuo Wang, Anqi Wang, Sujun Jiang, Xuzhen Qin*, Zucheng Ye*, Zhiyuan Hu*, Zihua Wang*. Glioblastoma cell-derived exosomes functionalized with peptides as efficient nanocarriers for synergistic chemotherapy of glioblastoma with improved biosafety. Nano Research, 2023, 16 (12): 13283-13293. (IF: 9.5，卓越计划“领军”期刊)

4.Ying Zhou#, Jinmei Zhou#, Xiaopeng Hao#, Haoyuan Shi#, Xuejie Li, Anqi Wang, Zhiyuan Hu*, Yanlian Yang*, Zefei Jiang*, Tao Wang*. Efficacy relevance of PD-L1 expression on circulating tumor cells in metastatic breast cancer patients treated with anti-PD-1 immunotherapy. Breast Cancer Research and Treatment, 2023, 200 (2): 281-291.

5.Ying Zhou#, Jinmei Zhou#, Jinyi Xiao#, Yuehua Wang#, Hao Wang, Haoyuan Shi, Chunyan Yue, Fei Jia, Ping Li, Zhiyuan Hu*, Yanlian Yang*, Zefei Jiang*, Tao Wang*. Prognostic Relevance of Estrogen Receptor Status in Circulating Tumor Cells in Breast Cancer Patients Treated With Endocrine Therapy. Frontiers in Oncology, 2022, 12: 866293.

6.Ying Zhou#, Long Wang#, Chaojia Wang, Yilin Wu, Dongmei Chen, Tae Ho Lee*, Potential implications of hydrogen peroxide in the pathogenesis and therapeutic strategies of gliomas. Archives of Pharmacal Research, 2020, 43 (2): 187-203.

7.Long Wang#, Xindong Shui#, Yuelin Diao, Duoting Chen, Ying Zhou*（周莹）, Tae Ho Lee*. Potential Implications of miRNAs in the Pathogenesis, Diagnosis, and Therapeutics of Alzheimer's Disease. International Journal of Molecular Sciences, 2023, 24 (22): 16259.

8.Long Wang#, Ying Zhou#, Dongmei Chen, Tae Ho Lee*. Peptidyl-Prolyl Cis/Trans Isomerase Pin1 and Alzheimer's Disease. Frontiers in Cell and Developmental Biology, 2020, 8: 355.

9.Haoyuan Shi#, Benliang Liu#, Jianhu Zhang#, Ying Zhou#, Zhiyuan Hu*, Xiuli Zhang*. Application of Artificial Intelligence Modeling Technology Based on Fluid Biopsy to Diagnose Alzheimer's Disease. Frontiers in Aging Neuroscience, 2021, 13: 768229.

教学成果

1.独立指导学生获得全国大学生基础医学创新研究大赛总决赛“金奖”1项，被评为“优秀指导教师”

2.指导学生获得全国大学生基础医学创新研究大赛总决赛“铜奖”1项

3.指导学生获得全国大学生基础医学创新研究大赛中南赛区省级一等奖2项

境外学术会议口头报告

1.18th Chinese International Peptide Symposium (CPS), Hong Kong, China, June 30th - July 2nd, 2024.

（更新于2025年7月）