孙建东 讲师
硕士生导师,组织学与胚胎学系
联系邮箱:jiandongsun12138@fjmu.edu.cn
个人简介
孙建东,男,讲师,硕士生导师。熟女a片 人体解剖与组织胚胎学专业获医学博士学位。现主持福建省联合创新基金、熟女a片 高层次人才科研启动项目各1项。近年来以共同第一作者/共同通讯作者发表SCI论文10篇,其中2区以上论文8篇。指导研究生获福建省基础医学研究生创新大赛学术墙报(博士组)一等奖,指导本科生获熟女a片 基础医学创新论坛暨实验设计大赛三等奖。
研究领域
男性不育与防治
主持/参与的项目
1.福建省科技厅,科技创新联合资金,Trps1在成年睾丸间质细胞发育过程中的调控作用及应用研究,15万元,2024.12-2027.12,主持;
2.熟女a片 ,熟女a片 高层次人才科研启动基金,组蛋白甲基化在成年睾丸间质细胞生成中的表达模式及作用机制,15万元,2024.12-2027.12,主持。
科研成果
1. Lian X#, Lin Z#, Hu W#, Chen Z, Luo S, Liao S, Liu Y, Wang S*, Sun J*. Trps1 targets Scarb1 to regulate cholesterol acquisition in mouse Leydig cells. Reprod Biol. 2025 Jun 18;25(3):101046. doi: 10.1016/j.repbio.2025.101046. (IF:2.0,中科院3区)
2. Sun J#, Lian X#, Lv C#, Li H, Lin Z, Luo S, Liu Y, Xu Y, Jiang X, Xu W, Liao S, Chen Z, Wang S*. Trps1 acts as a regulator of Sf-1 transcription and testosterone synthesis in mouse Leydig cells. Cell Biol Toxicol. 2023 Dec;39(6):3141-3157. doi: 10.1007/s10565-023-09823-8. (IF:6.1,中科院1区)
3. Sun J#, Li H#, Lv C# Draz E, Liu Y, Lin Z, Hu W, Mo K, Lin J, Xu W, Wang S*. Trps1 targets Ccnd1 to regulate mouse Leydig cell proliferation. Andrology. 2021 Nov;9(6):1923-1933. doi: 10.1111/andr.13072.(IF:4.456,中科院1区)
4. Sun J#, Xu W#, Zheng S#, Lv C, Lin J, Chen S, Qiu Y, Jiang X, Draz E, Wang S*. Icariin promotes mouse Leydig cell testosterone synthesis via the Esr1/Src/Akt/Creb/Sf-1 pathway. Toxicol Appl Pharmacol. 2022 Apr 15;441:115969. doi: 10.1016/j.taap.2022.115969. (IF:3.8,中科院2区)
5. Sun J#, Wang D#, Lin J#, Liu Y, Xu L, Lv R, Mo K, Lian X, Xie M, Xu S, Wang S*. Icariin protects mouse Leydig cell testosterone synthesis from the adverse effects of di(2-ethylhexyl) phthalate. Toxicol Appl Pharmacol. 2019 Sep 1;378:114612. doi: 10.1016/j.taap.2019.114612. (IF:3.347,中科院2区)
6. Wang X, Sun J#, Liu Y, Lin Z, Jiang X, Ye Y, Lv C, Lian X, Xu W, Luo S, Liao S, Chen Z, Wang S*. Trps1 predicts poor prognosis in advanced high grade serous ovarian carcinoma. Int J Cancer. 2024 May 1;154(9):1639-1651. doi: 10.1002/ijc.34844. (IF:6.4,中科院2区TOP)
7. Lv C, Sun J#, Ye Y, Lin Z, Li H, Liu Y, Mo K, Xu W, Hu W, Draz E, Wang S*. Long noncoding RNA EIF1AX-AS1 promotes endometrial cancer cell apoptosis by affecting EIF1AX mRNA stabilization. Cancer Sci. 2022 Apr;113(4):1277-1291. doi: 10.1111/cas.15275. (IF:5.7,中科院2区)
8. Liu Y, Sun J#, Su Y, Lin J, Lv C, Mo K, Xu S, Wang S*. Nuclear-localized eukaryotic translation initiation factor 1A is involved in mouse preimplantation embryo development. J Mol Histol. 2021 Oct;52(5):965-973. doi: 10.1007/s10735-021-10014-0. (IF:3.156,中科院3区)
9. Jiang X, Xu W, Sun J#, Lin J, Lin Z, Lian X, Liao S, Luo S, Liu Y*, Wang S*. Trps1 regulates mouse zygotic genome activation and preimplantation embryo development via the PDE4D/AKT/CREB signaling pathway. Cell Biol Toxicol. 2025 Feb 20;41(1):48. doi: 10.1007/s10565-025-09999-1. (IF: 5.9,中科院1区)
10. Ye Y, Lv C, Sun J#, Lin Z, Liu Y, Huang Y, Chen Y, Li H, Lian X, Jiang X, Zhang S*, Wang S*. XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma. Oxid Med Cell Longev. 2022 Dec 22;2022:1361135. doi: 10.1155/2022/1361135. (IF: 7.31,中科院2区)
(更新于2025年7月)