谢李华

硕士生导师

联系邮箱：[email protected]

个人简介

谢李华，女，医学博士，硕士生导师，博士毕业于南方医科大学病原生物学专业。2020年8月以校第五层次B类人才入职于熟女a片 病原生物学系，研究方向为蚊媒传染病防控技术研究，主要从事登革热媒介白纹伊蚊对吡丙醚等杀虫剂的抗药性和生殖调控研究。目前，在国内外期刊上发表10余篇论文，其中以第一或通讯作者在Parasites & Vectors（Ⅱ区）、Pest Management Science（Ⅰ区）和 Journal of Organic Chemistry（Ⅱ区）等国际知名杂志发表论文7篇，以第一发明人获得2 项中国发明专利。主持含国家自然科学基金在内项目4项，其中，国家自然科学基金青年项目1项，福建省自然科学基金面上项目1项，熟女a片 高层次人才科研启动经费1项，福建省高校重点实验室开放课题1项。

研究领域

 蚊媒传染病防控

科研成果

[1] Cheng Wu# , Yahui Chen# , Chenhua Zheng , Xitong Huang , Yuyang Xie , Lingqun Lin , Xiuli Zhang* , Lihua Xie*（谢李华） . The Role of AaPGRP-LB in the Immune Response of Aedes albopictus Against Bacteria Infection. Int J Mol Sci. 2025 Feb 28;26(5):2188. doi: 10.3390/ijms26052188. PMID: 40076812; PMCID: PMC11900923.

[2] Shi-Yuan Lin# , Pei-Ling Ye , Ya-Hui Chen , Nan Zheng , Cheng Wu*, Li-Hua Xie *（谢李华）.Genetic structure and knockdown resistance (kdr) mutations in Aedes albopictus (Skuse) (Diptera: Culicidae): Implications for dengue fever transmission in southeastern China. PLoS One. 2025 Mar 26;20(3):e0320200. doi: 10.1371/journal.pone.0320200. PMID: 40138384;

[3] Ya-Hui Chen # , Cheng Wu # , Yu-Yang Xie , Yan-Hui Zhang , Xi-Tong Huang , Fen Hu* , Li-Hua Xie*（谢李华）. Krüppel homolog 1, a juvenile hormone transcription factor, regulates the reproduction and development of Aedes albopictus(Skuse) (Diptera: Culicidae). Parasitol Res. 2025 Mar 22;124(3):36. doi: 10.1007/s00436-025-08479-z. PMID: 40119177; PMCID: PMC11928384.

[4] Ling-qun Lin#, Ya-hui Chen#, Yi-fan Tian, Yu-sen Chen, Zhao-yang Zheng, Jing-xin Wu, Fen Hu*, Cheng Wu* & Li-Hua Xie*（谢李华）.Study on the cross-resistance of Aedes albopictus (Skuse) (Diptera: Culicidae) to deltamethrin and pyriproxyfen. Parasites Vectors 17, 403 (2024). //doi.org/10.1186/s13071-024-06485-1

[5] Yan-Hui Zhang; Li-Hua Xie（谢李华）; Jian li; Yan-Wei Qi; Jia-Jian Shi ; Classification andclinical significance of immunogenic cell death-related genes in Plasmodium falciparum infectiondetermined by integrated bioinformatics analysis and machine learning, Malar J, 2024,23(48)

[6] Ziqin Zhang , Yifeng Chen , Linrong He , Lihua Xie *（谢李华）, Zhitao Chen *. Regioselective Synthesis of Indole-Fused Seven-Membered N‑Heterocycles via Photoredox-Catalyzed Intramolecular Cyclization. J Org Chem. 2022Nov4;87(21):14394-14406. doi: 10.1021/acs.joc.2c01829. 

[7] Zhang YH, Su XZ, Li J, Shi JJ, Xie LH（谢李华）. Multicohort transcriptome analysis of whole blood identifies robust human response signatures in Plasmodium falciparum infections. Malar J. 2022 Nov 15;21(1):333. doi: 10.1186/s12936-022-04374-5. PMID: 36380373; PMCID: PMC9664782.

[8] Lihua Xie#（谢李华）, Wenqiang Yang, Hongmei Liu, Tong Liu, Yugu Xie, Feng Lin, Guofa Zhou, Xiaohong Zhou, Kun Wu, Jinbao Gu, Guiyun Yan, Xiao-Guang Chen*. Enhancing attraction of the vector mosquito Aedes albopictus by using a novel synthetic odorant blend. Parasit Vectors. 2019 Jul 30;12(1):382. doi: 10.1186/s13071-019-3646-x.

[9] Tong Liu#, Yu-Gu Xie#, Feng Lin#, Li-Hua Xie#（谢李华）, Wen-Qiang Yang, Xing-Hua Su, Chun-Quan Ou, Lei Luo, Qi Xiao, Lu Gan, Xiao-Guang Chen*. A long-lasting biological larvicide against the dengue vector mosquito Aedes albopictus. Pest Manag Sci. 2021 Feb;77(2):741-748. doi: 10.1002/ps.6069. Epub 2020 Sep 17.

[10] Hongmei Liu, Lihua Xie（谢李华）, Peng Cheng , Jiabao Xu , Xiaodan Huang , Haifang Wang , Xiao Song , Lijuan Liu , Huaiwei Wang , Jingxuan Kou , Guiyun Yan , Xiao-Guang Chen* , Maoqing Gong* . Trends in insecticide resistance in Culex pipiens pallens over 20 years in Shandong, China. Parasit Vectors. 2019 Apr 11;12(1):167. doi: 10.1186/s13071-019-3416-9.

[11] Tong Liu , Wen-Qiang Yang , Yu-Gu Xie , Pei-Wen Liu , Li-Hua Xie（谢李华）, Feng Lin , Chen-Ying Li , Jin-Bao Gu , Kun Wu , Gui-Yun Yan , Xiao-Guang Chen* . Construction of an efficient genomic editing system with CRISPR/Cas9 in the vector mosquito Aedes albopictus. Insect Sci. 2019 Dec;26(6):1045-1054. doi: 10.1111/1744-7917.12645. Epub 2018 Nov 22.

[12] Hongmei Liu, Tong Liu, Li-Hua Xie（谢李华）, Xiaoming Wang , Yuhua Deng , Chun-Hong Chen , Anthony A James , Xiao-Guang Chen* . Functional analysis of Orco and odorant receptors in odor recognition in Aedes albopictus. Parasit Vectors. 2016 Jun 27;9(1):363. doi: 10.1186/s13071-016-1644-9.

已授权专利：

  1.发明专利：谢李华,陈晓光*.一种诱蚊剂（专利号：ZL 201610688318.2）（第一发明人，20190820授权）

  2.发明专利：谢李华,陈晓光*.一种诱蚊产卵剂及其应用（专利号：ZL 201810990168.X）（第一发明人，20210427授权）

（更新于2025年7月）